PropanaMide, N-(4-iodophenyl)-2-Methyl- synthesis
- Product Name:PropanaMide, N-(4-iodophenyl)-2-Methyl-
- CAS Number:161204-67-7
- Molecular formula:C10H12INO
- Molecular Weight:289.11
Yield:161204-67-7 97.1%
Reaction Conditions:
with pyridine in acetonitrile at 0 - 20; for 3 h;Reagent/catalyst;
Steps:
16 Preparation example 16: preparing N-isobutyryl-4-iodoaniline
The to 4-iodoaniline (5.0 g, 22.8 mmol) dissolved in acetonitrile (25 ml) in. The mixture of the obtained cooling to 0 °C the following, adding pyridine (1.85 ml). Then the isobutyryl chloride (2.3 ml, 22.8 mmol) added to the drops in the mixture. After the completion of the addition, the resultant reaction mixture of 3 hours. After the end of the reaction, the obtained mixture into ice water (70 ml) in, a solid precipitated, filtering. The resulting filter cake is dried to obtain 6.4 g white solid (yield: 97.1%).
References:
CN105384739,2016,A Location in patent:Paragraph 0357; 0358; 0359
4406-41-1
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