Termitomycamide E synthesis
1synthesis methods
- Product Name:Termitomycamide E
- CAS Number:1177258-62-6
- Molecular formula:C26H41NO2
- Molecular Weight:399.61
Yield:1177258-62-6 77%
Reaction Conditions:
Stage #1: linoleic acidwith 1,1'-carbonyldiimidazole in dichloromethane at 20; for 1 h;Inert atmosphere;
Stage #2: tyrosamine in dichloromethane at 20; for 2 h;Inert atmosphere;
References:
Wyffels, Leonie;Muccioli, Giulio G.;De Bruyne, Sylvie;Moerman, Lieselotte;Sambre, Johan;Lambert, Didier M.;De Vos, Filip [Journal of Medicinal Chemistry,2009,vol. 52,# 15,p. 4613 - 4622] Location in patent:experimental part