Thionicotinamide synthesis
- Product Name:Thionicotinamide
- CAS Number:4621-66-3
- Molecular formula:C6H6N2S
- Molecular Weight:138.19
100-54-9
562 suppliers
$5.00/10g
4621-66-3
225 suppliers
$13.00/5g
Yield:4621-66-3 97%
Reaction Conditions:
with hydrogenchloride;thiophosphate sodium salt hydrate in water;water-d2; pH=6.5 at 50; for 24 h;Sealed tube;
Steps:
Standard Procedure for Thiolysis
General procedure: Na3PSO3·xH2O (≥90% purity, 0.320 mmol, 64 mg) was dissolvedin degassed 10% D2O in H2O (0.5 mL) in an Eppendorf tube andthe pH was lowered to 6.5 (5.0 in the case of 26) using degassedHCl. The nitrile was added (0.080 mmol), and the volume madeup to 1 mL with degassed 10% D2O. The reaction was sealed andheated at 50 °C for 24 h taking time points at 8 and 24 h.
References:
Ritson, Dougal J.;Xu, Jiangfeng;Sutherland, John D. [Synlett,2017,vol. 28,# 1,art. no. ST-2016-S0500-C,p. 64 - 67]
98-92-0
1285 suppliers
$5.00/5g
4621-66-3
225 suppliers
$13.00/5g