trans-4-MethoxycyclohexanaMine HCl synthesis
- Product Name:trans-4-MethoxycyclohexanaMine HCl
- CAS Number:61367-41-7
- Molecular formula:C7H15NO.ClH
- Molecular Weight:165.66
760958-17-6
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61367-41-7
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Yield:61367-41-7 91%
Reaction Conditions:
with hydrogenchloride in 1,4-dioxane at 0; for 20 h;
Steps:
2.06.2
(2) To a solution of tert-butyl(trans-4-methoxycyclohexyl)carbamate (2.33 g, 10.2 mmol) in 1,4-dioxane (10 mL) was added hydrogen chloride in 1,4-dioxane (4N, 10.0 mL, 40.0 mmol) at 0° C. After being stirred for 20 hour, diethyl ether (100 mL) was added. The precipitate was collected and washed with diethyl ether to give trans-4-methoxycyclohexylamine hydrochloride (the compound of Reference Example 2.06 listed in the Table of Reference Examples as described hereinafter) as colorless crystals (1.54 g, 91%).
References:
US2011/160206,2011,A1 Location in patent:Page/Page column 28
167081-25-6
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61367-41-7
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111300-06-2
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61367-41-7
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56239-26-0
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61367-41-7
56 suppliers
$55.00/1g