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Technical Data Sheet (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone

Compound Information
Product Name: (1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone
CAS No.: 128517-07-7
Molecular Formula: C24H36N4O6S2
Molecular Weight: 540.7
Storage: Store at -20°C
Revision Date: 2026-04-27
Analytical Information
Tests Specifications
Description Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended
IUPAC Name Cyclo[(2Z)- 2- amino- 2- butenoyl- L- valyl- (3S,4E)- 3- hydroxy- 7- mercapto- 4- heptenoyl- D- valyl- D- cysteinyl], cyclic (3- 5) disulfide
Form powder
Color white to beige
Solubility Soluble in DMSO (up to 10 mg/ml).
HPLC Shows 99.9% purity
1H NMR Pass test
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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