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Technical Data Sheet 1-(3-(difluoromethyl)isothiazol-5-yl)-3-(2-fluoro-5-(hydroxymethyl)pyridin-4-yl)urea

Compound Information
Product Name: 1-(3-(difluoromethyl)isothiazol-5-yl)-3-(2-fluoro-5-(hydroxymethyl)pyridin-4-yl)urea
CAS No.: 2270879-17-7
Molecular Formula: C11H9F3N4O2S
Molecular Weight: 318.27
Storage: Powder -20°C 3 years; 4°C 2 years
In solvent -80°C 6 months; -20°C 1 month
Revision Date: 2026-04-15
Analytical Information
Tests Specifications
Description BRM/BRG1 ATP Inhibitor-1 is an orally active inhibitor (IC50 below 5 nM) of Brahma Homolog (BRM)?/SMARCA2 ATPase activity for the treatment of Brahma Related Gene 1 (BRG1)?/SMARCA4-?Mutant cancers.
Solubility DMSO: soluble
1H NMR Pass test
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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