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Technical Data Sheet 8-Chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-[2-(hexahydro-1H-azepin-1-yl)ethyl]-1H-1,2,3-triazol-4-yl]methyl]amino]-3-Quinolinecarbonitrile
Compound Information
Product Name:
8-Chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[[[1-[2-(hexahydro-1H-azepin-1-yl)ethyl]-1H-1,2,3-triazol-4-yl]methyl]amino]-3-Quinolinecarbonitrile
CAS No.:
915365-57-0
Molecular Formula:
C27H27Cl2FN8
Molecular Weight:
553.46
Storage:
Store the product in sealed, cool and dry condition.
Revision Date:
2026-04-27
Analytical Information
| Tests | Specifications |
|---|---|
| Description | Cot inhibitor-1 (compound 28) is a selective tumor progression loci-2 (Tpl2) kinase inhibitor with an IC50 of 28 nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC50 of 5.7 nM. |
| Form | Powder |
| Color | Light yellow to yellow |
| Purity | >98% |
| General tips | For obtaining a higher solubility, please warm the tube at 37 degrees Celsius (98.6 degrees Fahrenheit) and shake it in the ultrasonic bath for a while. |
| Solubility | DMSO 25 mg/mL |
| 1H NMR | Pass test |
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