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Technical Data Sheet Daptomycin
Compound Information
Product Name:
Daptomycin
CAS No.:
103060-53-3
Molecular Formula:
C72H101N17O26
Molecular Weight:
1620.67
Storage:
Store at < -20 °C
Revision Date:
2026-04-15
Analytical Information
| Tests | Specifications |
|---|---|
| Appearance | Pale yellow to yellow powder |
| Water Content (Karl Fisher) | ≤ 5% |
| pH | 3.0 -4.5 |
| Yeast and Mold | ≤ 50 cfu/g |
| Specific Rotation | [a]D20= 17 -25 ° |
| Residual Solvents | Methanol : ≤ 3000 ppm, Ethanol : ≤ 5000 ppm, Ethyl Acetate : ≤ 5000 ppm |
| Bacterial Endotoxins | ≤ 0.2 EU/mg |
| Microbial Count | ≤ 100 cfu/g (TAMC) |
| Related Substances | Anhydro-Daptomycin : ≤ 2%, Beta Isomer-Daptomycin : ≤ 0.5%, Lactone hydrolysis : ≤ 0.5%, RS-5/6 : ≤ 1%, Ethyl-Daptomycin : ≤ 0.8%, Asp-cyclized-Daptomycin : ≤ 0.35%, Any other individual impurity : ≤ 0.15%, Total impurities : ≤ 5% |
| Residue On Ignition | ≤ 0.1% |
| Assay (anhydrous basis) | 95 -102% |
| MS | Pass test |
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