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Technical Data Sheet Leniolisib

Compound Information
Product Name: Leniolisib
CAS No.: 1354690-24-6
Molecular Formula: C21H25F3N6O2
Molecular Weight: 450.46
Storage: Powder -20°C 3 years; 4°C 2 years
In solvent -80°C 6 months; -20°C 1 month
Revision Date: 2026-04-15
Analytical Information
Tests Specifications
Description Leniolisib (CDZ173) is a first-in-class (first-in-class), potent, selective PI3Kδ inhibitor with an IC50 value of 11 nM. Leniolisib has the potential for immunodeficiency disorders treatment.
Solubility DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.11(Max Conc. mM)
DMSO:71.67(Max Conc. mg/mL);159.09(Max Conc. mM)
Ethanol:16.5(Max Conc. mg/mL);36.63(Max Conc. mM)
1H NMR Pass test
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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