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Technical Data Sheet MK8245
Compound Information
Product Name:
MK8245
CAS No.:
1030612-90-8
Molecular Formula:
C17H16BrFN6O4
Molecular Weight:
467.25
Storage:
Store the product in sealed, cool and dry condition.
Revision Date:
2026-04-27
Analytical Information
| Tests | Specifications |
|---|---|
| Description | MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. |
| Form | solid |
| Color | White to off-white |
| Purity | >98% |
| General tips | For obtaining a higher solubility, please warm the tube at 37 degrees Celsius (98.6 degrees Fahrenheit) and shake it in the ultrasonic bath for a while. |
| Solubility | DMSO 90 mg/mL |
| NMR | Pass test |
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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