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Technical Data Sheet PF-06446846 HYDROCHLORIDE

Compound Information
Product Name: PF-06446846 HYDROCHLORIDE
CAS No.: 1632250-50-0
Molecular Formula: C22H21Cl2N7O
Molecular Weight: 470.36
Storage: Powder -20°C 3 years; 4°C 2 years
In solvent -80°C 6 months; -20°C 1 month
Revision Date: 2026-04-15
Analytical Information
Tests Specifications
Description PF-06446846 hydrochloride is a selective orally active PCSK9 inhibitor that appears to act by causing the ribosome to stall when synthesizing PCSK9.
Solubility DMSO : 250 mg/mL (531.52 mM)
1H NMR Pass test
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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