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Technical Data Sheet Ripasudil hydrochloride dihydrate

Compound Information
Product Name: Ripasudil hydrochloride dihydrate
CAS No.: 887375-67-9
Molecular Formula: C15H21ClFN3O3S
Molecular Weight: 377.86
Storage: Store the product in sealed, cool and dry condition.
Revision Date: 2026-04-27
Analytical Information
Tests Specifications
Description Ripasudil (K-115) hydrochloride dihydrate is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.
Form solid
Color White to off-white
Purity >98%
General tips For obtaining a higher solubility, please warm the tube at 37 degrees Celsius (98.6 degrees Fahrenheit) and shake it in the ultrasonic bath for a while.
Solubility 10 mM in DMSO
NMR Pass test
Disclaimer: This information relates only to the specific material designated and may not be valid for such material used in combination with anyother materials or in any other process. Such information is to be the best of the company's knowledge and believed accurate and reliable as of thedate indicated. However, no representation, warranty or guarantee of any kind, express or implied, is made as to its accuracy, reliability orcompleteness and we assume no responsibility for any loss, damage or expense, direct or consequential, arising out of use. It is the user'sresponsibility to satisfy himself as to the suitableness & completeness of such information for his own particular use.
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