| Identification | Back Directory | [Name]
Acetamide, N-[2-[[[4-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-5-chloro-2-methoxyphenyl]methyl]amino]ethyl]- | [CAS]
2159063-12-2 | [Synonyms]
PD-1/PD-L1-IN-22
Acetamide, N-[2-[[[4-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-5-chloro-2-methoxyphenyl]methyl]amino]ethyl]- | [Molecular Formula]
C25H26BrClN2O3 | [MOL File]
2159063-12-2.mol | [Molecular Weight]
517.84 |
| Hazard Information | Back Directory | [Uses]
PD-1/PD-L1-IN-22 (Example 2) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-22 blocks PD-1/PD-L1 with the IC50 of 0.732 μM. PD-1/PD-L1-IN-22 can be used for the research of cancers, infectious diseases and autoimmune diseases[1]. | [References]
[1] Phenylate derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202276A1. |
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