| Identification | Back Directory | [Name]
Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- | [CAS]
2159138-01-7 | [Synonyms]
PD-1/PD-L1-IN-20
Benzonitrile, 3-[[5-[(2-bromo[1,1'-biphenyl]-3-yl)methoxy]-4-chloro-2-[[(2-hydroxyethyl)amino]methyl]phenoxy]methyl]- | [Molecular Formula]
C30H26BrClN2O3 | [MOL File]
2159138-01-7.mol | [Molecular Weight]
577.9 |
| Hazard Information | Back Directory | [Uses]
PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases[1]. | [References]
[1] Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202273A1. |
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