| Identification | Back Directory | [Name]
Benzeneacetamide, α-[[(2S)-2-(4-cyanophenyl)propyl]amino]-N-[5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]-, (αS)- | [CAS]
2374971-82-9 | [Synonyms]
(S,S)-CPI-1612
Benzeneacetamide, α-[[(2S)-2-(4-cyanophenyl)propyl]amino]-N-[5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]-, (αS)- | [Molecular Formula]
C27H26N6O | [MOL File]
2374971-82-9.mol | [Molecular Weight]
450.53 |
| Chemical Properties | Back Directory | [Boiling point ]
719.1±60.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
12.12±0.70(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
(S,S)-CPI-1612 is the isomer of CPI-1612 (HY-136285), and can be used as an experimental control. CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity[1]. | [References]
[1] Wang F, et al. Microstructure of poly(gamma-glutamic acid) produced by Bacillus subtilis consisting of clusters of D- and L-glutamic acid repeating units. J Agric Food Chem. 2008 Jun 11;56(11):4225-8. DOI:10.1021/jf8001262 |
|
|