| Chemical Properties | Back Directory | [Boiling point ]
821.1±65.0 °C(Predicted) | [density ]
1.180±0.06 g/cm3(Predicted) | [solubility ]
DMSO: soluble
Methanol: soluble | [form ]
A solid | [pka]
3.50±0.10(Predicted) | [Sequence]
Phe-{d-Val}-Val-{d-Phe} |
| Hazard Information | Back Directory | [Description]
Bilaid A is a tetrapeptide agonist of the μ-opioid receptor (Ki = 3.1 μM using HEK293 cell membranes expressing the human receptor) that has been found in Penicillium.1 It inhibits forskolin-induced cAMP accumulation in HEK293 cells expressing the human μ-opioid receptor by 21% when used at a concentration of 10 μM. | [Uses]
Bilaid A is a μ-opioid receptor agonist that can be extracted from Penicillium. The Ki value is 3.1 μM. Bilaid A can be used in pain research[1]. | [References]
1. Dekan, Z., Sianati, S., Yousuf, A., et al. A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-opioid receptor Proc. Natl. Acad. Sci. USA 116(44),22353-22358(2019). |
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ChemeGen
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18818260767 |
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https://www.chemegen.com |
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Fuan Bio
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15002819872 |
| Website: |
fuanbio.com |
| Company Name: |
TargetMol
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400-821-0310 15002144251 |
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www.targetmol.cn/ |
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