| Identification | Back Directory | [Name]
Androst-4-ene-3,11-dione-16,16,17-d3, 17-hydroxy-, (17β)- | [CAS]
2479914-03-7 | [Synonyms]
16,16,17-2H3]-11-Keto testosterone
Androst-4-ene-3,11-dione-16,16,17-d3, 17-hydroxy-, (17β)- | [Molecular Formula]
C19H26O3 | [MOL File]
2479914-03-7.mol | [Molecular Weight]
302.41 |
| Hazard Information | Back Directory | [Uses]
11-Ketotestosterone-[16,16,17-d3] is used in the analysis of 52 C19 and C21 steroids by UPC2-MS/MS and characterization of the C11-oxy steroid metabolome in serum. | [References]
[1] TAKAFUMI YAMAGUCHI Masahiro S Hironobu Watanuki. Effects of estradiol, progesterone and testosterone on the function of carp, Cyprinus carpio, phagocytes in vitro[J]. Comparative Biochemistry and Physiology C-toxicology & Pharmacology, 2001, 129 1: Pages 49-55. DOI: 10.1016/s1532-0456(01)00176-4
[2] GODWIN J. Neuroendocrinology of sexual plasticity in teleost fishes[J]. Frontiers in Neuroendocrinology, 2010, 31 2: Pages 203-216. DOI: 10.1016/j.yfrne.2010.02.002
[3] PER-ERIK OLSSON. Molecular cloning and characterization of a nuclear androgen receptor activated by 11-ketotestosterone.[J]. Reproductive Biology and Endocrinology, 2005, 3: 37. DOI: 10.1186/1477-7827-3-37
[4] DESMARé VAN ROOYEN . CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway[J]. Journal of Steroid Biochemistry and Molecular Biology, 2020, 199: Article 105614. DOI: 10.1016/j.jsbmb.2020.105614 |
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