| Identification | Back Directory | [Name]
1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)- | [CAS]
2563861-90-3 | [Synonyms]
1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)- | [Molecular Formula]
C41H40N10O5 | [MOL File]
2563861-90-3.mol | [Molecular Weight]
752.82 |
| Hazard Information | Back Directory | [Uses]
PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. PROTAC BTK Degrader-3 has the potential for?B-cell malignancies, including chronic lymphoid malignancies research[1]. | [References]
[1] Zhangchen, et al. Salt of compound for degrading btk, crystal form thereof, and use thereof in medicine. Patent WO2022052950A1. |
|
|