| Identification | Back Directory | [Name]
1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, 2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethyl- | [CAS]
2719749-28-5 | [Synonyms]
1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, 2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethyl- | [Molecular Formula]
C18H20N4O2 | [MOL File]
2719749-28-5.mol | [Molecular Weight]
324.38 |
| Chemical Properties | Back Directory | [Boiling point ]
489.2±45.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
9.20±0.23(Predicted) | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Uses]
(Rac)-lunresertib (compound 181) is a potent membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor with an IC50 of <10 nM. (Rac)-lunresertib (compound 181) has anticancer effects[1]. | [Biological Activity]
(Rac)-RP-6306 (compound 181) is a potent Myt1 inhibitor with an IC50 of <10 nM. Myt1-IN-4 has anticancer effects[1]. | [IC 50]
PKMYT1 | [References]
[1]. Daniel Durocher, et al. Methods of using myt1 inhibitors. WO2021195782A1. |
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