| Identification | Back Directory | [Name]
1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, 2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethyl-, (1R)- | [CAS]
2719793-91-4 | [Synonyms]
1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, 2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethyl-, (1R)- | [Molecular Formula]
C18H20N4O2 | [MOL File]
2719793-91-4.mol | [Molecular Weight]
324.38 |
| Chemical Properties | Back Directory | [Boiling point ]
489.2±45.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 200 mg/mL (616.56 mM; Need ultrasonic) | [form ]
Solid | [pka]
9.20±0.23(Predicted) | [color ]
Off-white to gray |
| Hazard Information | Back Directory | [Uses]
(R)-lunresertib is a membrane-associated tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1) (Gene name PKMYT1) inhibitor, with IC50 of 1360 nM. (R)-lunresertib can be used in the study of Myt1-mediated cancers[1]. | [Biological Activity]
(R)-RP-6306 (183) can be used for the research of Myt1 mediated diseases and kinds of cancer for slowing the progression of cancer[1]. | [IC 50]
PKMYT1 | [References]
[1]. Daniel Durocher, et al. Methods of using myt1 inhibitors. Pantent WO2021195782A1. |
|
|