ChemicalBook--->CAS DataBase List--->98648-05-6

98648-05-6

98648-05-6 Structure

98648-05-6 Structure
IdentificationBack Directory
[Name]

BENZYL 6-OXOHEXYLCARBAMATE
[CAS]

98648-05-6
[Synonyms]

BENZYL 6-OXOHEXYLCARBAMATE
Benzyl 6-Oxohexylcarbamate DISCONTINUED
[Molecular Formula]

C14H19NO3
[MDL Number]

MFCD12031811
[MOL File]

98648-05-6.mol
[Molecular Weight]

249.31
Chemical PropertiesBack Directory
[Boiling point ]

412.7±38.0 °C(Predicted)
[density ]

1.079±0.06 g/cm3(Predicted)
[pka]

12.69±0.46(Predicted)
Hazard InformationBack Directory
[Description]

Benzyl (6-oxohexyl)carbamate is a PEG linker containing an aldehyde group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The aldehyde can be used in PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
[Uses]

Benzyl (6-oxohexyl)carbamate is a linker containing an aldehyde group and a benzyl (Cbz) protecting group. The aldehyde can react with hydrazine or hydrazide to form a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
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