98648-05-6
中文名稱
(6-氧己基)氨基甲酸芐酯
英文名稱
BENZYL 6-OXOHEXYLCARBAMATE
CAS
98648-05-6
分子式
C14H19NO3
分子量
249.31
MOL 文件
98648-05-6.mol
98648-05-6 結(jié)構(gòu)式
基本信息
中文別名
(6-氧己基)氨基甲酸芐酯(6-氧代己基)氨基甲酸芐酯
英文別名
BENZYL 6-OXOHEXYLCARBAMATEBenzyl 6-Oxohexylcarbamate DISCONTINUED
所屬類別
有機(jī)原料：羧酸類化合物及衍生物物理化學(xué)性質(zhì)
沸點(diǎn)412.7±38.0 °C(Predicted)
密度1.079±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)12.69±0.46(Predicted)
應(yīng)用領(lǐng)域
用途一
Benzyl (6-oxohexyl)carbamate is a PEG linker containing an aldehyde group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The aldehyde can be used in PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.