1126366-36-6
中文名稱
化合物 T26723
英文名稱
N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide
CAS
1126366-36-6
分子式
C25H24N4O2
分子量
412.48
MOL 文件
1126366-36-6.mol
1126366-36-6 結(jié)構(gòu)式
基本信息
中文別名
化合物 T26723 英文別名
AZD8542AZD-8542
AZD 8542
N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide
物理化學(xué)性質(zhì)
沸點572.5±50.0 °C(Predicted)
密度1.18±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)13.32±0.70(Predicted)
應(yīng)用領(lǐng)域
用途一
AZD8542 is an antagonist of Smoothened (SMO), with potential as an oncology therapeutic. It is a novel Hedgehog (Hh) pathway antagonist on tumor progression with an emphasis on the role of the stroma compartment.