114-90-9
114-90-9 結(jié)構(gòu)式
基本信息
中文別名
雙復(fù)磷 英文別名
bh6bu-6
luh6
lueh6
D009768
Obidoxim
TOXOGONIN
luh(sub6)
toxobidin
Obidoxime
所屬類別
原料藥：解毒藥物理化學(xué)性質(zhì)
熔點(diǎn)216-219oC dec.
儲(chǔ)存條件-20°C冷凍
溶解度Methanol (Slightly), Water (Slightly)
形態(tài)powder or crystals
顏色Off-White to Light Beige
BRN4117377
穩(wěn)定性穩(wěn)定的。與強(qiáng)氧化劑不相容。
InChI1S/C14H14N4O3.2ClH/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;;/h1-10H,11-12H2;2*1H
InChIKeyZIFJVJZWVSPZLE-UHFFFAOYSA-N
SMILES[Cl-].[Cl-].O\N=C\c1cc[n+](COC[n+]2ccc(cc2)\C=N\O)cc1
安全數(shù)據(jù)
WGK Germany2
RTECS號(hào)UU6825000
存儲(chǔ)類別11 - Combustible Solids
毒性LD50 in mice, rats (mg/kg): 70, 133 i.v.; 150, 225 i.p.; >2240, >4000 orally; in mice (mg/kg): 172 i.m. (Erdman, Engelhard)
雙復(fù)磷價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-W011108 | 雙復(fù)磷 Obidoxime dichloride | 114-90-9 | 5 mg | 250元 |
| 2026/06/05 | HY-W011108 | 雙復(fù)磷 Obidoxime dichloride | 114-90-9 | 10 mg | 400元 |
常見問題列表
生物活性
Obidoxime dichloride 是一種非全譜肟試劑，可作為有機(jī)磷類神經(jīng)毒劑中毒的解毒劑。Obidoxime dichloride 可活化被沙林蛋白抑制的乙酰膽堿酯酶 (AChE)，降低沙林蛋白的急性毒性。體內(nèi)研究
Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD 50 of 57.7 mg/kg after administration of sarin, and it reduces reduces acute toxicity of sarin was evaluated.
| Animal Model: | NMRI male mice |
| Dosage: | 10 mg/kg |
| Administration: | Intramuscular injection |
| Result: | Was effective in reactivating sarin-inhibited acetylcholinesterase (AChE). |