1210330-64-5
中文名稱
雷西納德雜質(zhì)J
英文名稱
Lesinurad Impurity J
CAS
1210330-64-5
分子式
C14H10BrN3O2S
分子量
364.22
MOL 文件
1210330-64-5.mol
更新日期
2025/05/25 22:01:07
1210330-64-5 結(jié)構(gòu)式
基本信息
中文別名
萊辛鈉雜質(zhì)E雷西納德雜質(zhì)J
雷西那德雜質(zhì)9
雷西納德雜質(zhì)I:去環(huán)丙基雷西納德
英文別名
Lesinurad Impurity JResinad Impurity I: Decyclocycloresinad
Lesinurad Impurity 9 (Lesinurad Impurity E)
2-((5-bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid
Lesinurad Impurity 1/2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid
所屬類別
分析化學(xué)：藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品物理化學(xué)性質(zhì)
沸點617.6±57.0 °C(Predicted)
密度1.69±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)2.91±0.10(Predicted)
應(yīng)用領(lǐng)域
用途一
2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.