1289942-55-7
中文名稱
1289942-55-7
英文名稱
4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-
CAS
1289942-55-7
分子式
C20H18F4N4O2
分子量
422.38
MOL 文件
1289942-55-7.mol
更新日期
2025/12/16 13:40:55
1289942-55-7 結構式
基本信息
中文別名
恩扎盧胺雜質(zhì)A恩雜魯胺雜質(zhì)W
恩雜魯胺雜質(zhì)19
英文別名
Enzalutamide Impurity WEnzalutamide Impurity 26
4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-
物理化學性質(zhì)
沸點616.2±55.0 °C(Predicted)
密度1.36±0.1 g/cm3(Predicted)
溶解度DMSO (Slightly), Methanol (Slightly)
酸度系數(shù)(pKa)13?+-.0.70(Predicted)
形態(tài)Solid
顏色White to Off-White
應用領域
用途一
4-[[2-[[4-Cyano-3-(trifluoromethyl)phenyl]amino]-1,1-dimethyl-2-oxoethyl]amino]-2-fluoro-N-methyl-benzamide is an impurity of Enzalutamide (M199800), an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.