1443331-94-9
中文名稱
[2H6]-恩雜魯胺
英文名稱
[2H6]-Enzalutamide
CAS
1443331-94-9
分子式
C21H16F4N4O2S
分子量
464.44
MOL 文件
1443331-94-9.mol
更新日期
2024/09/27 12:11:49
1443331-94-9 結構式
基本信息
中文別名
恩雜魯胺-[D6][2H6]-恩雜魯胺
英文別名
[2H6]-EnzalutamideEnzalutamide D6Q: What is Enzalutamide D6 Q: What is the CAS Number of Enzalutamide D6 Q: What is the storage condition of Enzalutamide D6 Q: What are the applications of Enzalutamide D6
應用領域
用途一
Isotope labelled MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.常見問題列表
概述
[2H6]-恩雜魯胺 是一種氘標記的 Enzalutamide (MDV3100)。Enzalutamide 是一種雄激素受體 (AR) 拮抗劑，在 LNCaP 前列腺細胞中 IC50 為 36 nM。