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135531-86-1

中文名稱 CAMALEXIN
英文名稱 camalexin
CAS 135531-86-1
分子式 C11H8N2S
分子量 200.26
MOL 文件 135531-86-1.mol
更新日期 2026/05/25 13:08:19
135531-86-1 結(jié)構(gòu)式 135531-86-1 結(jié)構(gòu)式

基本信息

中文別名
植保素
35531-86-1
化合物CAMALEXIN
英文別名
camalexin
Camalexine
Camalexin >=98% (HPLC)
3-(Thiazol-2-yl)-1H-indole
1H-Indole, 3-(2-thiazolyl)-
3-(1,3-Thiazol-2-yl)-1H-indole, camalexin

物理化學(xué)性質(zhì)

沸點424.8±47.0 °C(Predicted)
密度1.336±0.06 g/cm3(Predicted)
儲存條件2-8°C
溶解度在DMSO中的溶解度為20mg/mL,澄清
酸度系數(shù)(pKa)15.49±0.30(Predicted)
形態(tài)粉末
顏色白色至淺棕色
InChI1S/C11H8N2S/c1-2-4-10-8(3-1)9(7-13-10)11-12-5-6-14-11/h1-7,13H
InChIKeyIYODIJVWGPRBGQ-UHFFFAOYSA-N
SMILESC12=CC=CC=C1NC=C2C3=NC=CS3

安全數(shù)據(jù)

危險性符號(GHS)有害 (GHS07)
GHS07
警示詞警告
危險性描述H302-H315-H319-H335
危險品標(biāo)志Xn,Xi
危險類別碼22-36/37/38
安全說明26-36/37/39-45
WGK Germany3
存儲類別11 - Combustible Solids
危險性類別Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
CAMALEXIN價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2026/06/05HY-119502RCAMALEXIN
Camalexin (Standard)
135531-86-15 mg1750元
2026/06/05HY-119502RCAMALEXIN
Camalexin (Standard)
135531-86-110 mg2800元
2026/06/05HY-119502RCAMALEXIN
Camalexin (Standard)
135531-86-125 mg5600元

常見問題列表

生物活性
Camalexin 是一種植物抗毒素,是從 Camelina sativa 和 Arabidopsis(十字花科植物)中分離出來的,具有抗菌,抗真菌,抗增殖和抗癌活性。Camalexin 可誘導(dǎo)活性氧 (ROS) 的產(chǎn)生。
靶點

Reactive oxygen species (ROS)

體外研究

Camalexin shows antiproliferative activity against a human breast cancer cell line.
For the oomycetes Phytophthora and Pythium Nep1-like proteins (necrosis and ethylene-inducing peptide 1-like proteins) are the initial triggers of Camalexin synthesis and formation of reactive oxygen species (ROS). ROS appear to be of general relevance for Camalexin formation. Chemical induction of ROS, such as by application of acifluorfen, coincided with Camalexin synthesis. In a screen for enhanced susceptibility to Alternaria brassicicola the esa1 mutant is identified, which shows delayed Camalexin induction. Particularly in response to ROS inducing agents reduced Camalexin levels are synthesized. This crucial role for ESA1 is confirmed by the inability of esa1 mutants to synthesize Camalexin in response to Leptosphaeria maculans . An additional mutant that exhibits greatly reduced Camalexin accumulation is ups1 , which is isolated on the basis of diminished expression of a tryptophan biosynthetic enzyme.

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