1374639-78-7
中文名稱
瑞博司可里布中間體
英文名稱
1-Piperazinecarboxylic acid, 4-[6-[[7-cyclopentyl-6-[(diMethylaMino)carbonyl]-7H-pyrrolo[2,3-d]pyriMidin-2-yl]aMino]-3-pyridinyl]-, 1,1-diMethylethyl ester
CAS
1374639-78-7
分子式
C28H38N8O3
分子量
534.65
MOL 文件
1374639-78-7.mol
更新日期
2026/04/27 12:58:57
1374639-78-7 結(jié)構(gòu)式
基本信息
中文別名
瑞博西尼雜質(zhì)E瑞博西尼 N-1
瑞博司可里布中間體
LEE011中間體5
4-(6-(7-環(huán)戊基-6-(二甲基甲?；?-7H-吡咯并[2,3-D]嘧啶-2-基氨基吡啶-3-基)哌嗪-1-羧酸叔丁酯
(6-((7-環(huán)戊基-6-(二甲基氨基甲?；?-7H-吡咯并[2,3-D]嘧啶-2-基)氨基)吡啶-3-基)哌嗪-1-甲酸叔丁酯
4- [6-(7-環(huán)戊基-6-二甲基氨基甲酰基-7H-吡咯并[2,3-D]嘧啶-2-基氨基) - 吡啶-3-基] - 哌嗪-1-羧酸叔丁酯
4-?[6-?[[7-?環(huán)戊基-?6-?[(二甲氨基)?羰基]?-?7H-?吡咯[2,?3-?D]?嘧啶-?2-?基]?氨基]?-?3-?吡啶基]?-?1-?哌嗪羧酸1,1-二甲基乙基酯
英文別名
4-[6-(7-Cyclopentyl-6-dimethylcarbamoyl-7H-pyrrolo[2,3-d]pyr...tert-butyl 4-(6-(7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)pyridin-3-yl)piperazine-1-carboxylate
4-[6-(7-Cyclopentyl-6-dimethylcarbamoyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-pyridin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester
1-Piperazinecarboxylic acid, 4-[6-[[7-cyclopentyl-6-[(diMethylaMino)carbonyl]-7H-pyrrolo[2,3-d]pyriMidin-2-yl]aMino]-3-pyridinyl]-, 1,1-diMethylethyl
4-[6-[[7-cyclopentyl-6-[(dimethylamino)carbonyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-pyridinyl]-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester
1-Piperazinecarboxylic acid, 4-[6-[[7-cyclopentyl-6-[(diMethylaMino)carbonyl]-7H-pyrrolo[2,3-d]pyriMidin-2-yl]aMino]-3-pyridinyl]-, 1,1-diMethylethyl ester
1-Piperazinecarboxylic acid, 4-[6-[[7-cyclopentyl-6-[(diMethylaMino)carbonyl]-7H-pyrrolo[2,3-d]pyriMidin-2-yl]aMino]-3-pyridinyl]-, 1,1-diMethylethyl ester-2
所屬類別
醫(yī)藥中間體：原料藥中間體物理化學(xué)性質(zhì)
沸點(diǎn)761.2±70.0 °C(Predicted)
密度1.28g/cm3 at 20℃
蒸氣壓0-0Pa at 20-25℃
儲(chǔ)存條件under inert gas (nitrogen or Argon) at 2–8 °C
酸度系數(shù)(pKa)6.25±0.30(Predicted)
形態(tài)Solid:bulk
外觀Light yellow to brown Solid
LogP3.6-3.8 at 35℃ and pH7-9
