1445379-59-8
中文名稱(chēng)
1 - ((2R,3R,4R,5R)-4 - ((叔丁基二甲基硅烷基)氧基)-3-氟-5-(羥甲基)
英文名稱(chēng)
3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine
CAS
1445379-59-8
分子式
C15H25FN2O5Si
分子量
360.45
MOL 文件
1445379-59-8.mol
更新日期
2024/03/19 22:24:38
1445379-59-8 結(jié)構(gòu)式
基本信息
中文別名
1 - ((2R,3R,4R,5R)-4 - ((叔丁基二甲基硅烷基)氧基)-3-氟-5-(羥甲基)1-((2R,3R,4R,5R)-4-((叔丁基二甲基硅烷基)氧基)-3-氟-5-(羥甲基)四氫呋喃-2-基)嘧啶-2,4(1H,3H)-二酮
英文別名
3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine2'-Deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluorouridine
Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-
1-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
所屬類(lèi)別
醫(yī)藥中間體：雜環(huán)化合物物理化學(xué)性質(zhì)
熔點(diǎn)182 - 185° C
密度1.23±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C Freezer, Under inert atmosphere
溶解度Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated)
酸度系數(shù)(pKa)9.39±0.10(Predicted)
形態(tài)固體
顏色白色至灰白色
InChIInChI=1S/C15H25FN2O5Si/c1-15(2,3)24(4,5)23-12-9(8-19)22-13(11(12)16)18-7-6-10(20)17-14(18)21/h6-7,9,11-13,19H,8H2,1-5H3,(H,17,20,21)/t9-,11-,12-,13-/m1/s1
InChIKeyKKWGVZHEXOEALO-OJAKKHQRSA-N
SMILESOC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](F)[C@@H]1O[Si](C(C)(C)C)(C)C
