146669-29-6
中文名稱
(+/-)MCPG
英文名稱
(RS)-MCPG
CAS
146669-29-6
分子式
C10H11NO4
MDL 編號
MFCD00210205
分子量
209.2
MOL 文件
146669-29-6.mol
146669-29-6 結(jié)構(gòu)式
基本信息
中文別名
(+/-)MCPG 英文別名
(+/-)-ALPHA-METHYL-(4-CARBOXYPHENYL)GLYCINE[+/-]-MCPG
(RS)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
(RS)-A-METHYL-4-CARBOXYPHENYLGLYCINE
(RS)-MCPG
(+/-)MCPG
(+/-)-A-METHYL-(4-CARBOXYPHENYL)GLYCINE
(+-)-A-METHYL-4-CARBOXYPHENYLGLYCINE MET ABOTROPIC GLUTAMAT
所屬類別
生物化工：甘氨酸類衍生物物理化學(xué)性質(zhì)
沸點425.3±40.0 °C(Predicted)
密度1.390±0.06 g/cm3(Predicted)
儲存條件Keep in dark place,Inert atmosphere,Room temperature
溶解度DMSO : 6 mg/mL (28.68 mM; Need ultrasonic and warming)
酸度系數(shù)(pKa)1.76±0.10(Predicted)
形態(tài)粉末
顏色白色
InChI1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)
InChIKeyDNCAZYRLRMTVSF-UHFFFAOYSA-N
SMILESCC(N)(C(O)=O)c1ccc(cc1)C(O)=O
CAS 數(shù)據(jù)庫146669-29-6(CAS DataBase Reference)
(+/-)MCPG價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/12/22 | HY-100371 | (RS)-MCPG | 146669-29-6 | 1 mg | 304元 |
| 2025/12/22 | HY-100371 | (+/-)MCPG (RS)-MCPG | 146669-29-6 | 5mg | 690元 |
| 2025/12/22 | HY-100371 | (+/-)MCPG (RS)-MCPG | 146669-29-6 | 10mM * 1mLin DMSO | 700元 |
常見問題列表
生物活性
(RS)-MCPG (alpha-MCPG) 是一種競爭性和選擇性 I/II 組代謝型谷氨酸受體 (mGluR) 拮抗劑。(RS)-MCPG 阻斷 TBS 誘導(dǎo)的幼年和新生大鼠海馬神經(jīng)元的轉(zhuǎn)變。靶點
group I/group II mGluR
體外研究
MCPG can block group I (mGluR1 and mGluR5) and group II receptors (mGluR2 and mGluR3).
體內(nèi)研究
(RS)-MCPG (alpha-MCPG; 500 μM) blocks the TBS-induced shifts in EGABA in either juvenile or neonatal neurons.
Pretreatment with the low dose of (RS)-MCPG (25 nM; i.c.; daily; 5 days) significantly attenuates amphetamine-induced locomotor activity in 10-day-old male and female rats of Sprague-Dawley descent.