1496552-28-3
中文名稱
氨基酸反轉(zhuǎn)異構(gòu)體
英文名稱
D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester
CAS
1496552-28-3
分子式
C22H29FN3O9P
分子量
529.45
MOL 文件
1496552-28-3.mol
更新日期
2025/11/03 09:45:20
1496552-28-3 結(jié)構(gòu)式
基本信息
中文別名
索非布韋雜質(zhì)C索非布韋雜質(zhì)03
氨基酸反轉(zhuǎn)異構(gòu)體
索福斯布韋雜質(zhì)24
Y008005-D
英文別名
SRDSofosbuvir impurity C
2(R)-Methyl Sofosbuvir
Sofosbuvir (2R)-Methyl Impurity
D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester
D-Alanine, N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester
isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl
isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alanite
isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-Dalaninate
(2R)-isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
所屬類別
分析化學(xué)：藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品物理化學(xué)性質(zhì)
密度1.41±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)9.39±0.10(Predicted)
形態(tài)Solid
顏色Light yellow to yellow
常見(jiàn)問(wèn)題列表
概述
氨基酸反轉(zhuǎn)異構(gòu)體 是 Sofosbuvir 的一種雜質(zhì)。Sofosbuvir 是一種 HCV RNA 復(fù)制抑制劑，具有有效的抗丙型肝炎病毒 (HCV) 活性。