1504588-00-4
1504588-00-4 結構式
基本信息
中文別名
化合物 T23709 英文別名
NAB 2alphaSYN-IN-NAB2
NAB2 >=98% (HPLC)
alphaSYN inhibitor-NAB2
alphaSYN inhibitor NAB2
N-[(2-Chlorophenyl)methyl]-1-(2,5-dimethylphenyl)-1H-benzimidazole-5-carboxamide
N-[(2-chlorophenyl)methyl]-1-(2,5-dimethylphenyl)-1H-1,3-benzodiazole-5-carboxamide
物理化學性質
密度1.24±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度DMSO: 5 mg/mL
酸度系數(shù)(pKa)13.04±0.46(Predicted)
形態(tài)結晶固體
顏色White to off-white
應用領域
用途一
alphaSYN-IN-NAB2 is an inhibitor of α-synuclein mutations. It acts by reversing the α-synuclein-induced pathological phenotype in Parkinson's disease cortical neurons and promoting E3 ubiquitin ligase Rsp5/Nedd4-dependent endosomal transport..