17057-04-4
17057-04-4 結(jié)構(gòu)式
基本信息
4-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)BENZOIC ACID
4-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-BENZOIC ACID
4-MALEIMIDOBENZOIC ACID
AKOS B006486
AKOS MSC-0031
ART-CHEM-BB B006486
N-(4-CARBOXYPHENYL)MALEIMIDE
N-(4-Benzoic acid)maleimide
4-(2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-yl)benzoic acid
4-(2,5-Dioxo-1H-pyrrole-1-yl)benzoic acid
4-(2,5-Dioxo-1-pyrrolyl)benzoic acid
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrole-1-yl)benzoic acid
INCA-12
物理化學(xué)性質(zhì)
制備方法
108-31-6
150-13-0
17057-04-4
（1）在500mL三頸燒瓶中裝配機(jī)械攪拌器、溫度計(jì)和恒壓滴液漏斗。向燒瓶中加入35g馬來酸酐（0.357mol）和100mL丙酮，于20℃下攪拌至完全溶解。同時(shí)，將49g對(duì)氨基苯甲酸（0.357mol）溶于250mL丙酮中，制備成透明溶液。隨后，將對(duì)氨基苯甲酸的丙酮溶液通過恒壓滴液漏斗緩慢滴加到三頸燒瓶中。滴加完畢后，繼續(xù)攪拌反應(yīng)1小時(shí)。反應(yīng)完成后，進(jìn)行抽濾（回收溶劑），用適量溶劑洗滌固體產(chǎn)物，隨后進(jìn)行重結(jié)晶和干燥，得到黃色晶體N-(4-羧基苯基)馬來酰亞胺酸77.28g，收率為92%，純度為99.3%（HPLC分析）。
參考文獻(xiàn)：
[1] Patent: CN107286072, 2017, A. Location in patent: Paragraph 0017; 0018; 0019
[2] Revue Roumaine de Chimie, 2008, vol. 53, # 9, p. 743 - 752
[3] Acta Crystallographica Section C: Crystal Structure Communications, 2011, vol. 67, # 2, p. o67-o70
[4] Patent: CN106243118, 2016, A. Location in patent: Paragraph 0029
[5] Revue Roumaine de Chimie, 2001, vol. 46, # 10, p. 1167 - 1173