189956-45-4
中文名稱
4-N[2(4-羥基嘧啶基)]氨基苯腈
英文名稱
4-((4-Oxo-1,4-dihydropyriMidin-2-yl)aMino)benzonitrile
CAS
189956-45-4
分子式
C11H8N4O
分子量
212.21
MOL 文件
189956-45-4.mol
更新日期
2026/07/29 17:32:29
189956-45-4 結(jié)構(gòu)式
基本信息
中文別名
利匹韋林雜質(zhì)G4-羥基-2-(4-氰基苯胺基)嘧啶
4-N[2(4-羥基嘧啶基)]氨基苯腈
4-[(4-羥基-2-嘧啶)氨基]苯腈
4-[(4-羥基-2-嘧啶基)氨基]苯腈
4-[(4-羥基-2-嘧啶基)氨基]苯甲腈
英文別名
Rilpivirine Lactam Impurity4-((4-Oxo-1,4-dihydropyrimidin-2-yl)
4-[(4-Hydroxy-pyrimidin-2-yl)amino]-benzonitr
4-N[2(4-HYDROXYPYRIMIDINYL)]AMINOBENZONITRILE
4-[(6-oxo-1H-pyrimidin-2-yl)amino]benzonitrile
4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile
4-(6-Oxo-1,6-dihydropyrimidin-2-ylamino)benzonitrile
4-((4-Oxo-1,4-dihydropyriMidin-2-yl)aMino)benzonitrile
4-[(1,4-Dihydro-4-oxo-2-pyrimidinyl)amino]benzonitrile
Benzonitrile, 4-[(1,4-dihydro-4-oxo-2-pyriMidinyl)aMino]-
所屬類別
醫(yī)藥中間體：羥基嘧啶物理化學性質(zhì)
熔點>300°C
密度1.31±0.1 g/cm3(Predicted)
蒸氣壓0-0Pa at 20-25℃
儲存條件2-8°C
溶解度DMSO (Slightly), Methanol (Slightly)
酸度系數(shù)(pKa)8.66±0.40(Predicted)
形態(tài)Solid
顏色Pale Brown to Brown
LogP0.9 at pH6.6
CAS 數(shù)據(jù)庫189956-45-4
![4-[(4-羥基-2-嘧啶基)氨基]苯腈的合成路線](http://www.hezefdc.com/NewsImg/2020-04-07/2020471122435972.png)