1973402-05-9
中文名稱
度魯特韋雜質(zhì) 3
英文名稱
Dolutegravir Impurity 3
CAS
1973402-05-9
分子式
C20H19F2N3O5
分子量
419.38
MOL 文件
1973402-05-9.mol
更新日期
2026/05/26 16:50:21
1973402-05-9 結(jié)構(gòu)式
基本信息
中文別名
多替拉韋雜質(zhì)3多替拉韋雜質(zhì)51
英文別名
Dolutegravir Impurity 3Dolutegravir impurity A
Dolutegravir Impurity 51
DolutegravirImpurity9SodiumSalt
(R)-N-(2,4-difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]p
(R)-N-(2,4-difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
N-[(2,4-Difluorophenyl)methyl]-1,8-dihydro-9-hydroxy-2-[(1R)-3-hydroxy-1-methylpropyl]-1,8-dioxo-2H-pyrido[1,2-a]pyrazine-7-carboxamide
2H-Pyrido[1,2-a]pyrazine-7-carboxamide, N-[(2,4-difluorophenyl)methyl]-1,8-dihydro-9-hydroxy-2-[(1R)-3-hydroxy-1-methylpropyl]-1,8-dioxo-
Dolutegravir impurity 2/2H-Pyrido[1,2-a]pyrazine-7-carboxamide, N-[(2,4-difluorophenyl)methyl]-1,8-dihydro-9-hydroxy-2-[(1R)-3-hydroxy-1-methylpropyl]-1,8-dioxo-
所屬類別
分析化學(xué)：藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品物理化學(xué)性質(zhì)
熔點(diǎn)95-100°C
沸點(diǎn)662.3±55.0 °C(Predicted)
密度1.51±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C Freezer, Under inert atmosphere
溶解度可溶于DMSO（少許）、甲醇（少許）
酸度系數(shù)(pKa)4.50±1.00(Predicted)
形態(tài)固體
顏色黃色
InChIKeyNQVIDZANHVWALI-LLVKDONJSA-N
SMILESC12=C(O)C(=O)C(C(NCC3=CC=C(F)C=C3F)=O)=CN1C=CN([C@H](C)CCO)C2=O