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223769-64-0

中文名稱 羥基脒雙(甲磺酸)
英文名稱 HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe]
CAS 223769-64-0
更新日期 2026/05/28 12:19:28
分子式 C18H24N4O7S2
分子量 472.5
MOL 文件 223769-64-0.mol
223769-64-0 結構式 223769-64-0 結構式

基本信息

中文別名
羥基脒雙(甲磺酸)
羥芪巴脒*DNA和RNA染料*
英文別名
Fluoro-Gold
Hydroxystilbamidine *CAS 223769-64-0*
HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe]
4-[2-[4-(Aminoiminomethyl)phenyl]ethenyl]-3-hydroxybenzenecarboximidamide bis(methanesulfonate)
HydroxystilbaMidine bis(Methanesulfonate) [Know as FluoroGold(TM), TM of FluorochroMe]

物理化學性質(zhì)

儲存條件2-8°C
溶解度可溶于水
形態(tài)粉末狀
顏色Light yellow to yellow
InChI1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
InChIKeyYGNSQKCULHSJDC-HFPMQDOPSA-N
SMILESCS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N

安全數(shù)據(jù)

危險性符號(GHS)有害 (GHS07)
GHS07
警示詞警告
危險性描述H315-H319-H335
危險品標志Xi
危險類別碼36/37/38
安全說明26-36
WGK Germany3
存儲類別11 - Combustible Solids
危險性類別Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
羥基脒雙(甲磺酸)價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2025/12/22HY-108166A羥基脒雙(甲磺酸)
Hydroxystilbamidine bis(methanesulfonate)
223769-64-01 mg850元
2025/12/22HY-108166A羥基脒雙(甲磺酸)
Hydroxystilbamidine bis(methanesulfonate)
223769-64-05 mg2850元
2025/12/22HY-108166A羥基脒雙(甲磺酸)
Hydroxystilbamidine bis(methanesulfonate)
223769-64-010 mg4500元

常見問題列表

生物活性
Hydroxystilbamidine bis(methanesulfonate) 是一種能夠結合 DNA 和 RNA 的染料, 也被發(fā)現(xiàn)是細胞核糖核酸酶的強效抑制劑。
體外研究

It is found that the trypanocidal dye Hydroxystilbamidine bis(methanesulfonate) permits the recovery of mRNA after polysome released with Nonidet P-40 (NP-40). Sucrose gradient analysis of detergent-lysed postnuclear supernates is used to analyze the size distribution of NP-40-released polysomes. The heparin gradient shows some polyribosomes, whereas the Hydroxystilbamidine bis(methanesulfonate) gradient shows a remarkably large peak of very heavy polyribosomes. This peak is obtained reproducibly if Hydroxystilbamidine bis(methanesulfonate) is present before the addition of NP-40.

體內(nèi)研究

Hydroxystilbamidine bis(methanesulfonate) is an effective suppressor of the plaque-forming cell (PFC) response when given before sheep erythrocytes (SRBC) stimulation. Hydroxystilbamidine bis(methanesulfonate) depresses the plaque response of the treated mice. Fewer PFC are observed in Hydroxystilbamidine bis(methanesulfonate)-treated mice throughout the experiment, but the level of suppression decreases with time. By day 14, the number of PFC observed in both the Hydroxystilbamidine bis(methanesulfonate) treated mice and the control group is essentially at the background level.

"223769-64-0" 相關產(chǎn)品信息
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