2316-26-9
2316-26-9 結構式
基本信息
3,4-二甲氧基肉桂酸
3,4-二甲氧基苯乙烯酸
3,4-二甲氧基苯丙烯酸
3,4-二甲氧基肉桂酸
3,4-二甲氧基苯乙烯酸, PREDOMINANTLY TRANS
3-(3,4-DIMETHOXYPHENYL)-2-PROPENOIC ACID
3-(3,4-DIMETHOXY-PHENYL)-ACRYLIC ACID
3',4'-DIMETHOXYCINNAMIC ACID
3,4-DIMETHOXYCINNAMIC ACID
AKOS BB/0042
AKOS BBS-00000090
AURORA 2809
DIMETHYLCAFFEIC ACID
(E)-3-(3,4-DIMETHOXYPHENYL)-2-PROPENOIC ACID
(E)-3-(3,4-DIMETHOXY-PHENYL)-ACRYLIC ACID
OTAVA-BB BB0107620014
RARECHEM BK HC T253
TIMTEC-BB SBB005722
(2E)-3-(3,4-Dimethoxyphenyl)-2-propenoic acid
2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-
3-(3,4-dimethoxyphenyl)propenoicacid
3,4-Dimethoxyphenyl-2-propenoic acid
3,4-Di-O-methylcaffeic acid
Cinnamic acid, 3,4-dimethoxy-
物理化學性質
安全數(shù)據(jù)
制備方法
141-82-2
120-14-9
2316-26-9
通用方法：在干燥的反應容器中，將藜蘆醛（500 mg，1.0當量）和丙二酸（981 mg，2.0當量）溶于二甲基甲酰胺（5 mL）中，隨后加入DABCO（105 mg，0.2當量）。將反應混合物在100-110°C下攪拌反應60-90分鐘。反應進程通過薄層色譜（TLC）監(jiān)測。反應完成后，將混合物緩慢倒入冰水中，用乙酸乙酯（3×10 mL）萃取。合并有機相，用無水硫酸鈉干燥，過濾并減壓濃縮。粗產(chǎn)物通過從氯仿/己烷混合溶劑中重結晶純化，得到3,4-二甲氧基肉桂酸，收率良好。
參考文獻：
[1] Organic Letters, 2016, vol. 18, # 5, p. 1182 - 1185
[2] Oriental Journal of Chemistry, 2012, vol. 28, # 4, p. 1725 - 1728
[3] Asian Journal of Chemistry, 2017, vol. 29, # 7, p. 1561 - 1564
[4] Journal of Heterocyclic Chemistry, 1987, vol. 24, # 6, p. 1589 - 1594
[5] RSC Advances, 2015, vol. 5, # 34, p. 26596 - 26603
知名試劑公司產(chǎn)品信息
3,4-Dimethoxycinnamic acid, 99%(2316-26-9)
3,4-Dimethoxycinnamic acid, predominantly trans, 99%(2316-26-9)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/07/06 | 11551 | 3,4-二甲氧基肉桂酸,主要為反式 3,4-Dimethoxycinnamic acid, 99%, predominantly trans isomer, Thermo Scientific Chemicals | 2316-26-9 | 5g | 239元 |
| 2026/07/06 | S9341 | 3,4-二甲氧基肉桂酸 3,4-Dimethoxycinnamic acid | 2316-26-9 | 25mg | 795.21元 |
| 2026/06/06 | D1728 | 3,4-二甲氧基肉桂酸 3,4-Dimethoxycinnamic Acid | 2316-26-9 | 25G | 200元 |
常見問題列表
3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 μM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells.
3,4-Dimethoxycinnamic acid (25, 50 and 100 μM) inhibits the expression levels of Nox4 and p22
phox
in L-02 cells.
3,4-Dimethoxycinnamic acid (25, 50 and 100 μM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells.
3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner.