253449-04-6
中文名稱
WISKOSTATIN
英文名稱
1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL
CAS
253449-04-6
分子式
C17H18Br2N2O
分子量
426.15
MOL 文件
253449-04-6.mol
更新日期
2025/10/22 10:56:11
253449-04-6 結(jié)構(gòu)式
基本信息
中文別名
威司他汀化合物WISKOSTATIN
1-(3,6-二溴-9H-咔唑-9-基)-3-(二甲基氨基)-2-丙醇
英文別名
WISKOSTATINWiskostatin - CAS 253449-04-6 - Calbiochem
1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol
3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol
1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL
9H-Carbazole-9-ethanol, 3,6-dibromo-α-[(dimethylamino)methyl]-
1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(dimethylamino)propan-2-ol 97%
9H-Carbazole-9-ethanol, 3,6-dibroMo-alpha-[(diMethylaMino)Methyl]-
3,6-Dibromo-9-[3-(dimethylamino)-2-hydroxyprop-1-yl]-9H-carbazole, 3-(3,6-Dibromo-9H-carbazol-9-yl)-N,N-dimethyl-2-hydroxypropylamine
所屬類別
生物化工：激動(dòng)劑抑制劑物理化學(xué)性質(zhì)
熔點(diǎn)153-155
沸點(diǎn)320.2±22.0 °C(Predicted)
密度1.62±0.1 g/cm3(Predicted)
儲(chǔ)存條件2-8°C
溶解度DMSO：可溶10mg/mL，澄清
酸度系數(shù)(pKa)14.40±0.20(Predicted)
形態(tài)白色固體
顏色白色至米色
穩(wěn)定性從購買之日起 2 年內(nèi)保持穩(wěn)定。 DMSO 或乙醇溶液可在 -20℃ 下保存長達(dá) 3 個(gè)月。
InChI1S/C17H18Br2N2O/c1-20(2)9-13(22)10-21-16-5-3-11(18)7-14(16)15-8-12(19)4-6-17(15)21/h3-8,13,22H,9-10H2,1-2H3
InChIKeyXUBJEDZHBUPBKL-UHFFFAOYSA-N
SMILESCN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13
安全數(shù)據(jù)
警示詞危險(xiǎn)
危險(xiǎn)性描述H301-H413
危險(xiǎn)品標(biāo)志Xi,T
危險(xiǎn)類別碼25
安全說明45
危險(xiǎn)品運(yùn)輸編號UN 2811 6.1 / PGIII
WGK Germany3
Hazard NoteIrritant
危險(xiǎn)等級6.1
海關(guān)編碼2933998090
存儲(chǔ)類別6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
toxic compounds or compounds which causing chronic effects
危險(xiǎn)性類別Acute Tox. 3 Oral
Aquatic Chronic 4
Aquatic Chronic 4
應(yīng)用領(lǐng)域
用途1
一種選擇性的N-wasp抑制劑。Wiskostatin is a selective inhibitor of N-WASP, a ubiquitously expressed member of the Wiskott-Aldrich Syndrome protein (WASp) family that regulates actin polymerization. Wiskostatin inhibits actin-dependent cellular functions, including migration, transmembrane transport and phagocytosis.