30544-47-9
中文名稱
依托芬那酯
英文名稱
Etofenamate
CAS
30544-47-9
分子式
C18H18F3NO4
分子量
369.33
MOL 文件
30544-47-9.mol
更新日期
2026/07/16 08:22:42
30544-47-9 結(jié)構(gòu)式
基本信息
中文別名
依托芬那酯2[[3-(三氟甲基)苯基]氨基]-2-(羥乙氧基)乙基苯甲酸酯
2-(2-羥基乙氧基)乙基 2-[3-(三氟甲基)苯胺基]苯甲酸酯
英文別名
TV-485ReuMon
TVX-485
Rheumon
Bayrogel
Etofenamate
TrauMon Gel
Ethofenamate
EtofenaMate,TV-485
EtofenamateEtofenamate
所屬類別
原料藥：非甾抗炎藥物理化學(xué)性質(zhì)
熔點(diǎn)25°C
沸點(diǎn)bp.001 130-135°
密度1.2866 (estimate)
折射率nD25 1.564
儲(chǔ)存條件Refrigerator
溶解度Practically insoluble in water, miscible with ethanol (96 per cent) and with ethyl acetate.
酸度系數(shù)(pKa)14.32±0.10(Predicted)
形態(tài)neat
顏色Light yellow to yellow
穩(wěn)定性感光
主要應(yīng)用pharmaceutical (small molecule)
InChIInChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2
InChIKeyXILVEPYQJIOVNB-UHFFFAOYSA-N
SMILESC(OCCOCCO)(=O)C1=CC=CC=C1NC1=CC=CC(C(F)(F)F)=C1
安全數(shù)據(jù)
警示詞危險(xiǎn)
危險(xiǎn)性描述H301-H410
危險(xiǎn)品運(yùn)輸編號(hào)UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
WGK GermanyWGK 3
存儲(chǔ)類別6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
toxic compounds or compounds which causing chronic effects
危險(xiǎn)性類別Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Aquatic Acute 1
Aquatic Chronic 1
毒性LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi)