330785-84-7
中文名稱
(S)-4-(3-氯-4-甲氧基苯氨基)-5-羧基-2-(2-羥甲基-1-吡咯基)嘧啶
英文名稱
5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-
CAS
330785-84-7
分子式
C18H21ClN4O4
分子量
392.84
MOL 文件
330785-84-7.mol
更新日期
2026/01/10 12:34:52
330785-84-7 結(jié)構(gòu)式
基本信息
中文別名
阿伐那非雜質(zhì)N阿伐那非雜質(zhì)35
阿伐那非雜質(zhì)27
阿伐那非中間體3
AVANAFIL雜質(zhì)N
(S)-4-(3-氯-4-甲氧基苯氨基)
S-4-3-氯-4-甲氧基芐胺-5-羧基-2-2-羥甲基-1-吡咯基嘧啶
(S)-4-(3-氯-4-甲氧基苯氨基)-5-羧基-2-(2-羥甲基-1-吡咯基)嘧啶
(S)-4-(3-氯-4-甲氧基芐基氨基)-5-羧基-2-(2-羥甲基-1-吡咯烷基)嘧啶
(S)-4-[(3-氯-4-甲氧苯基)氨基]-2-[2-(羥基甲基) 吡咯-1-基]嘧啶-5-甲酸
英文別名
(S)-4-(3-Chloro-4-methoxybenzylamino)-5-carboxy-2-(2-hydroxy...(S)-4-(3-chloro-4-MethoxybenzylaMino)-5-carboxy-2-(2-hydroxyMethyl-1-pyrrolidinyl)pyriMidine
5-PYRIMIDINECARBOXYLIC ACID, 4-[[(3-CHLORO-4-METHOXYPHENYL)METHYL]AMINO]-2-[(2S)-2-(HYDROXYMETHYL)-
(S)-4-(3-Chloro-4-Methoxybenzyl)Amino)-2-(2-(Hydroxymethyl)Pyrolidin-1-Yl)Pyrimidine-5-Carboxylic Acid
(S)-4-((3-Chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)pyriMidine-5-carboxylic acid
4-(3-chloro-4-methoxybenzylamino) -2-((S)-2-(hydroxymethyl) pyrrolidin-1-yl)pyrimidine-5- carboxylic acid
4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid
4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-5-pyrimidinecarboxylic acid
5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-
所屬類別
醫(yī)藥中間體：嘧啶類化合物物理化學(xué)性質(zhì)
熔點(diǎn)>176oC (dec.)
沸點(diǎn)647.6±65.0 °C(Predicted)
密度1.415±0.06 g/cm3 (20 ºC 760 Torr)
儲存條件under inert gas (nitrogen or Argon) at 2–8 °C
溶解度可溶于DMSO（輕微）、甲醇（輕微、加熱）
酸度系數(shù)(pKa)1.80±0.36(Predicted)
形態(tài)固體
顏色白色
