34334-69-5
中文名稱
條葉薊素
英文名稱
6,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
CAS
34334-69-5
分子式
C17H14O7
分子量
330.29
MOL 文件
34334-69-5.mol
更新日期
2026/05/26 09:15:11
34334-69-5 結(jié)構(gòu)式
基本信息
中文別名
中國薊醇條葉薊素
英文別名
CIRSILIOLCrisiliol
Cirsiliol >=95% (HPLC)
3'-Hydroxy-6-methoxygenkwanin
3',4',5-Trihydroxy-6,7-dimethoxy
6-Methoxyluteolin 7-methyl ether
6-Hydroxyluteolin-6,7-dimethyl ether
6,7-DIMETHOXY-5,3',4'-TRIHYDROXYFLAVONE
6,7-DIMETHOXY-3',4',5-TRIHYDROXYFLAVONE
6,7-DIMETHOXY-3,4'',5-TRIHYDROXYFLAVONE 95+%
所屬類別
天然產(chǎn)物：黃酮類化合物物理化學(xué)性質(zhì)
熔點280-281.5℃ (methanol )
沸點616.1±55.0 °C(Predicted)
密度1.483±0.06 g/cm3(Predicted)
儲存條件2-8°C
溶解度Acetone: soluble; Chloroform: soluble; DMSO: soluble
酸度系數(shù)(pKa)6.31±0.40(Predicted)
形態(tài)粉末
顏色白色至米色
InChI1S/C17H14O7/c1-22-14-7-13-15(16(21)17(14)23-2)11(20)6-12(24-13)8-3-4-9(18)10(19)5-8/h3-7,18-19,21H,1-2H3
InChIKeyIMEYGBIXGJLUIS-UHFFFAOYSA-N
SMILES[o]1c2c([c](cc1c3cc(c(cc3)O)O)=O)c(c(c(c2)OC)OC)O
安全數(shù)據(jù)
條葉薊素價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/12/22 | HY-110399 | 條葉薊素 Cirsiliol | 34334-69-5 | 1 mg | 500元 |
| 2025/12/22 | HY-110399 | 條葉薊素 Cirsiliol | 34334-69-5 | 5 mg | 1100元 |
| 2025/12/22 | HY-110399 | 條葉薊素 Cirsiliol | 34334-69-5 | 10 mg | 1900元 |
常見問題列表
生物活性
Cirsiliol是有效和選擇性的5-脂氧合酶 (5-lipoxygenase) 抑制劑，并且是競爭性低親和力的苯二氮卓受體配體。靶點
|
5-Lipoxygenase
|
體外研究
In concentrations from 0.01 to 300 μM, cirsiliol causes concentration-dependent relaxation of rat isolated ileum. Cirsiliol may inhibit Ca 2+ influx but stimulates Ca 2+ release from intracellular stores. Treatment with rhamnetin or cirsiliol reduces the proliferation of NSCLC cells through the suppression of radiation-induced Notch-1 expression.
體內(nèi)研究
In xenograft mouse model, tumor volume is significantly reduced by combinational treatment with irradiation and rhamnetin or cirsiliol compared with irradiation alone.