3728-20-9
3728-20-9 結(jié)構(gòu)式
基本信息
D-TYROSINE-OME HCL
H-D-TYR-OME HCL
METHYL D-TYROSINATE HYDROCHLORIDE
H-D-Tyr-OMe·HCI
D-Tyrosine Methyl Ester HCl
H-D-Try-OMe-HCl
物理化學(xué)性質(zhì)
制備方法
67-56-1
556-02-5
3728-20-9
以甲醇和D-酪氨酸為原料合成(R)-2-氨基-3-(4-羥基苯基)丙酸甲酯鹽酸鹽的一般步驟：將(2R)-2-氨基-3-(4-羥基苯基)丙酸（49）（1.07 g，5.9 mmol）溶解于甲醇中，反應(yīng)完成后得到(2R)-2-氨基-3-(4-羥基苯基)丙酸甲酯（50）。產(chǎn)物表征數(shù)據(jù)如下：熔點(diǎn)176°C（文獻(xiàn)值一致）；1H NMR (DMSO-d6) δ: 6.82 (d, J = 8.4 Hz, 2H, ArH3'和ArH5'), 4.13 (t, J = 6.9 Hz, 1H, H2), 3.83 (s, 3H, OCH3), 3.22 (dd, J = 6.0, 14.4 Hz, 1H, 3Ha), 3.12 (dd, J = 6.9, 14.7 Hz, 1H, 3Hb)。質(zhì)譜（化學(xué)電離，正離子模式）m/z: 196（100%）[M+]。高分辨質(zhì)譜（HRMS）計(jì)算值C10H14NO3: 196.0974，實(shí)測值: 196.0985。
參考文獻(xiàn)：
[1] Organic Letters, 2002, vol. 4, # 2, p. 265 - 267
[2] Organic and Biomolecular Chemistry, 2007, vol. 5, # 4, p. 636 - 643
[3] Patent: WO2006/74501, 2006, A1. Location in patent: Page/Page column 152
[4] Tetrahedron, 2008, vol. 64, # 49, p. 11270 - 11290
[5] Organic and Biomolecular Chemistry, 2005, vol. 3, # 7, p. 1233 - 1239
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2026/07/06 | H63630 | D-酪氨酸甲酯鹽酸鹽，98％ D-Tyrosine methyl ester hydrochloride, 98% | 3728-20-9 | 25g | 1453元 |
| 2025/05/22 | H63630 | D-酪氨酸甲酯鹽酸鹽，98％ D-Tyrosine methyl ester hydrochloride, 98% | 3728-20-9 | 5g | 316元 |
| 2025/05/22 | XW37282093 | D-酪氨酸甲酯鹽酸鹽 methyl d-tyrosinate hydrochloride;d-tyrosine methyl ester hydrochloride;(r)-methyl 2-amino-3-(4-hydroxyphenyl)propionate hydrochloride;(r)-2-amino-3-(4-hydroxyphenyl)propionic acid methyl ester hydrochloride;h-d-tyr-ome·hcl | 3728-20-9 | 25G | 185元 |