4097-22-7
中文名稱
2',3'-雙脫氧腺苷
英文名稱
Dideoxyadenosine
CAS
4097-22-7
EINECS 編號
223-853-2
分子式
C10H13N5O2
MDL 編號
MFCD00010534
分子量
235.24
MOL 文件
4097-22-7.mol
更新日期
2026/07/03 17:36:04
4097-22-7 結(jié)構(gòu)式
基本信息
中文別名
2',3'-雙脫氧腺甙2',3'-雙脫氧腺苷
2,3-二脫氧腺苷
二脫氧腺(嘌呤核)苷
雙脫氧腺嘌呤核苷
英文別名
2',3'-DIDEOXYADENOSINEBETA-D-2',3'-DIDEOXYADENOSINE
DDA
DIDEOXYADENOSINE
2’,3’-dideoxy-adenosin
2',3'-Dideoxy-D-adenosine
9-(2,3-Dideoxy-beta-D-ribofuranosyl)adenine
2',3'-DIDEOXYADENOSINE extapure
[(2S,5R)-5-(6-Aminopurin-9-yl)oxolan-2-yl]methanol
NSC 98700
所屬類別
生物化工：脫氧核苷酸及其類似物物理化學性質(zhì)
熔點181-184 °C(lit.)
比旋光度D25 -25.2° (c = 1.01 in water)
沸點377.64°C (rough estimate)
密度1.2455 (rough estimate)
折射率-34 ° (C=1, H2O)
儲存條件2-8°C
溶解度DMF: 1 mg/mL; DMSO: 2 mg/mL; Ethanol: Slightly soluble
酸度系數(shù)(pKa)pKa 3.84(H2O t=25.0±0. I=0.01) (Uncertain)
形態(tài)粉末
顏色白色至灰白色
旋光度 (Optical Rotation)[α]/D -28.0±1.0
水溶解性43.2g/L(25 ºC)
Merck3101
BRN619924
InChIKeyWVXRAFOPTSTNLL-NKWVEPMBSA-N
CAS 數(shù)據(jù)庫4097-22-7(CAS DataBase Reference)
EPA化學物質(zhì)信息Adenosine, 2',3'-dideoxy- (4097-22-7)
安全數(shù)據(jù)
警示詞警告
危險性描述H341-H303
危險品標志C
危險類別碼34-36/37-22
WGK Germany2
RTECS號AU7358900
海關(guān)編碼29349990
毒性LD50 oral in mouse: 5gm/kg
2',3'-雙脫氧腺苷價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/07/06 | J64573 | 2',3'-二脫氧腺苷,98% 2',3'-Dideoxyadenosine, 98% | 4097-22-7 | 25mg | 1367元 |
| 2026/06/06 | D3065 | 2',3'-二脫氧腺苷 2',3'-Dideoxyadenosine | 4097-22-7 | 100MG | 2185元 |
| 2026/06/05 | HY-W013441R | 2',3'-雙脫氧腺苷 2',3'-Dideoxyadenosine (Standard) | 4097-22-7 | 5 mg | 300元 |
常見問題列表
生物活性
2',3'-Dideoxyadenosine 是 HIV 復(fù)制抑制劑。抗逆轉(zhuǎn)錄病毒活性?？共《净钚?[1]。靶點
HIV
體外研究
2',3'-Dideoxyadenosine inhibits HIV-1 and simian immunodeficiency virus (SIV) in MT-4 cells with EC 50 s of 5.27 and 5.3 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in human T-lymphocyte CEM cells with EC 50 s of 4 μM and 8 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in Molt 4/C8 cells with EC 50 s of 4 μM and 5.5 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in C8166 cells with EC 50 s of 17 μM and 22 μM, respectively. 2',3'-Dideoxyadenosine inhibits murine sarcoma virus (MSV) in C3H/3T3 cells with an EC 50 of 24 μM.