41179-33-3
中文名稱
CMPD1
英文名稱
2'-FLUORO-N-(4-HYDROXYPHENYL)-[1,1'-BIPHENYL]-4-BUTANAMIDE
CAS
41179-33-3
分子式
C22H20FNO2
分子量
349.4
MOL 文件
41179-33-3.mol
41179-33-3 結(jié)構(gòu)式
基本信息
中文別名
化合物CMPD14-(2'-氟-[1,1'-聯(lián)苯]-4-基)-N-(4-羥基苯基)丁酰胺
英文別名
SRA1CMD1
CMPD-1
MK2a Inhibitor
CMPD-1 (CMPD 1
Steroid receptor RNA activator 1
ANTI-SOX9 antibody produced in mouse
MK2a Inhibitor - CAS 41179-33-3 - Calbiochem
ANTI-SRA1 (C-TERM) antibody produced in rabbit
Monoclonal Anti-SOX9 antibody produced in mouse
物理化學(xué)性質(zhì)
熔點(diǎn)128-130 °C
沸點(diǎn)585.0±50.0 °C(Predicted)
密度1.229±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C
溶解度Soluble to 100 mM in DMSO and to 100 mM in ethanol
酸度系數(shù)(pKa)10.11±0.26(Predicted)
形態(tài)淡黃色固體
顏色Off-white to light brown
生物來(lái)源mouse
InChI1S/C22H20FNO2/c23-21-6-2-1-5-20(21)17-10-8-16(9-11-17)4-3-7-22(26)24-18-12-14-19(25)15-13-18/h1-2,5-6,8-15,25H,3-4,7H2,(H,24,26)
InChIKeyODYAQBDIXCVKAE-UHFFFAOYSA-N
SMILESFc1c(cccc1)c2ccc(cc2)CCCC(=O)Nc3ccc(cc3)O
CMPD1價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-108643 | CMPD1 | 41179-33-3 | 1 mg | 574元 |
| 2026/06/05 | HY-108643 | CMPD1 CMPD1 | 41179-33-3 | 5mg | 1244元 |
| 2026/06/05 | HY-108643 | CMPD1 CMPD1 | 41179-33-3 | 10mM * 1mLin DMSO | 1368元 |
常見問(wèn)題列表
生物活性
CMPD1 是一種選擇性且非 ATP 競(jìng)爭(zhēng)性的 p38 MAPK 介導(dǎo)的 MK2 磷酸化抑制劑，表觀 Ki (Kiapp) 值為 330 nM。靶點(diǎn)
Ki app : 330?nM (MK2 phosphorylation)
體外研究
CMPD1 does not inhibit p38 MAPK-mediated phosphorylation of other two substrates, MBP and ATF2.
CMPD1 induced mitotic arrest and apoptosis in U87 cells.
CMPD1 inhibits tubulin polymerisation in glioblastoma cells.