4199-10-4
中文名稱
鹽酸普奈洛爾
英文名稱
(S)-(-)-PROPRANOLOL HYDROCHLORIDE
CAS
4199-10-4
EINECS 編號(hào)
224-096-0
分子式
C16H22ClNO2
MDL 編號(hào)
MFCD00064547
分子量
295.8
MOL 文件
4199-10-4.mol
更新日期
2024/06/03 14:41:39
4199-10-4 結(jié)構(gòu)式
基本信息
中文別名
鹽酸普奈洛爾 英文別名
2S-(-)-PROPANOLOL HYDROCHLORIDE(S)-(-)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE
(S)-1-ISOPROPYLAMINO-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE
S-(-)-PROPANOLOL HCL
S(-)-PROPRANOLOL HCL
(S)-(-)-PROPRANOLOL HYDROCHLORIDE
(S)-PROPRANOLOL HYDROCHLORIDE
(S)-[2-hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride
2-Propanol, 1-(1-methylethyl)amino-3-(1-naphthalenyloxy)-, hydrochloride, (2S)-
2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (2S)- (9CI)
2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (S)-
L-(-)-Propranolol hydrochloride
l-Propranolol chlorhydrate
l-Propranolol hydrochloride
S-(-)-1-Isopropylamino-3-(1-naphthoxy)-2-propanol hydrochloride
S-PROPANOLOL
(S)-1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride
(S)-(-)-1-(1-Methylethylamino)-3-naphthalen-1-yloxy-propan-2-ol hydrochloride
(2S)-1-(1-Naphtyloxy)-3-(isopropylamino)-2-propanol·hydrochloric acid
物理化學(xué)性質(zhì)
熔點(diǎn)193-195 °C(lit.)
熔點(diǎn)193-195 °C(lit.)
儲(chǔ)存條件2-8°C
儲(chǔ)存條件2-8°C
溶解度ethanol: 10 mg/mL
溶解度乙醇：10 mg/mL
形態(tài)powder
形態(tài)粉末
顏色White to off-white
旋光度 (Optical Rotation)[α]25/D 25.5°, c = 1.0 in ethanol(lit.)
水溶解性溶于水至100mM
BRN3574966
InChI1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m0./s1
InChIKeyZMRUPTIKESYGQW-UQKRIMTDSA-N
SMILESCl[H].CC(C)NC[C@H](O)COc1cccc2ccccc12
CAS 數(shù)據(jù)庫4199-10-4(CAS DataBase Reference)
安全數(shù)據(jù)
應(yīng)用領(lǐng)域
用途1
The S-enantiomer of Propranolol (P831800). β鈭扐drenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).(S)-鹽酸普萘洛爾價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/12/22 | HY-B0573A | (S)-鹽酸普萘洛爾 (S)-(-)-Propranolol hydrochloride | 4199-10-4 | 50 mg | 400元 |
| 2025/12/22 | HY-B0573A | (S)-鹽酸普萘洛爾 (S)-(-)-Propranolol hydrochloride | 4199-10-4 | 10 mM * 1 mLin DMSO | 440元 |
| 2025/12/22 | HY-B0573A | (S)-鹽酸普萘洛爾 (S)-(-)-Propranolol hydrochloride | 4199-10-4 | 100mg | 650元 |
常見問題列表
生物活性
(S)-(-)-Propranolol hydrochloride 是一種腎上腺素能受體 (β-adrenergic receptor) 拮抗劑，針對(duì) β1，β2，和β3的 log Kd 值分別為 -8.16，-9.08 和 -6.93。(S)-(-)-Propranolol hydrochloride 可以用于高血壓，嗜鉻細(xì)胞瘤，心肌梗塞，心律不齊，心絞痛和肥大心肌病的相關(guān)研究。靶點(diǎn)
log Kd: -8.16 (β 1 -adrenergic receptor)log Kd: -9.08 (β 2 -adrenergic receptor)log Kd: -6.93 (β 3 -adrenergic receptor)