42079-78-7
42079-78-7 結(jié)構(gòu)式
基本信息
5-甲氧基黃酮,97%
METHOXYFLAVONE, 5-
5-methoxy-2-phenyl-4-benzopyrone
5-Methoxyflavone,97%
5-Methoxy-2-phenyl-4H-1-benzopyran-4-one
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/03/03 | S4782 | 5-甲氧基黃酮 5-methoxyflavone | 42079-78-7 | 25mg | 794.68元 |
| 2026/03/03 | S4782 | 5-甲氧基黃酮 5-methoxyflavone | 42079-78-7 | 1g | 7944.3元 |
| 2025/12/22 | HY-107790 | 5-甲氧基黃酮 5-Methoxyflavone | 42079-78-7 | 10 mg | 340元 |
常見問題列表
| Target | Value |
|
DNA polymerase β
() |
5-Methoxyflavone (compound 1) is identified as a candidate compound endowed with the ability to inhibit DNA pol-β in multiple and to prevent cell-cycle initiation and subsequent neuronal apoptosis in Aβ-challenged primary neuronal cultures. 5-methoxyflavone (10-30 μM) is able to significantly enhance toxicity of MMS on 92TAg cells. 5-Methoxyflavone (1 or 10 μM) significantly reduces polymerase activity on a gapped substrate.
5-Methoxyflavone (5-MF, 0-100 μg/mL) results in a time dependent reduction in the levels of antiapoptotic proteins cFLIP, Mcl-1 and an increase in the proapoptotic protein BAX. 5-MF induces both TRAIL-R1(DR4) and TRAIL-R2 (DR5) in a time-dependent manner.
5-Methoxyflavone (100, 150 mg/kg, i.p) significantly decreases the latency time to loss of righting reflex. 5-Methoxyflavone (50, 100 and 150 mg/kg, i.p) exhibits a significant and dose-dependent reduction in the spontaneous locomotor activity. 5-Methoxyflavone (50, 100 mg/kg, i.p) reduces the rearing response. 5-Methoxyflavone (100, 125 and 150 mg/kg, i.p) completely abolishesed the grooming response similar to diazepam treated animals.