42373-41-1
中文名稱
5'-ATP-K2
英文名稱
ADENOSINE 5'-TRIPHOSPHATE POTASSIUM SALT
CAS
42373-41-1
分子式
C10H14K2N5O13P3
分子量
583.36
MOL 文件
42373-41-1.mol
42373-41-1 結(jié)構(gòu)式
基本信息
中文別名
腺苷三磷酸二鉀鹽5'-三磷酸腺苷二鉀鹽
腺苷-5'-三磷酸二鉀鹽
二水合-5`-三磷酸腺苷二鉀鹽
英文別名
ATP·K25'-ATP-K2
ATP dipotassium
ATP POTASSIUM SALT
ADENOSINE 5'-TRIPHOSPHATE POTASSIUM SALT
ADENOSINE-5'-TRIPHOSPHATE DIPOTASSIUM SALT
adenosine 5'-triphosphate dipotassium*from bacter
ADENOSINE 5'-TRIPHOSPHATE DIPOTASSIUMFRO M BACTERIA
Adenosine 5μ-triphosphate dihydrate dipotassium salt
Adenosine 5'-(tetrahydrogen triphosphate), dipotassiuM salt
物理化學(xué)性質(zhì)
儲存條件−20°C
溶解度H2O: 50 mg/mL
形態(tài)powder
生物來源microbial
水溶解性H2O: 50mg/mL
InChIKeyYFPSRAQDZYNYPX-IDIVVRGQSA-L
SMILES[K+].[K+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
安全數(shù)據(jù)
警示詞警告
危險性描述H315-H319-H335
危險品標(biāo)志Xi
危險類別碼36/37/38
安全說明26-36
WGK Germany3
存儲類別11 - Combustible Solids
危險性類別Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Skin Irrit. 2
STOT SE 3
5'-ATP-K2價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-B2176C | 5'-ATP-K2 ATP dipotassium | 42373-41-1 | 50 mg | 300元 |
| 2026/06/05 | HY-B2176C | 5'-ATP-K2 ATP dipotassium | 42373-41-1 | 100 mg | 500元 |
常見問題列表
生物活性
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) 是體內(nèi)能量儲存和代謝的重要物質(zhì)，為代謝提供能量，同時在細(xì)胞中作為輔酶發(fā)揮作用。ATP dipotassium 是免疫和炎癥中重要的內(nèi)源性信號分子。體外研究
ATP dipotassium (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP dipotassium (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.
ATP dipotassium promotes neutrophil chemotaxis in vitro.
體內(nèi)研究
ATP dipotassium (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP dipotassium induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.
| Animal Model: | Four-week-old Kunming mice (18-22 g) |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal injection, before bacterial ( E. coli ) challenge |
| Result: | Protected mice from bacterial infection. |