477888-48-5
中文名稱
3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophene-2-carboxylic acid
英文名稱
3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophene-2-carboxylic acid
CAS
477888-48-5
分子式
C11H11NO2S
分子量
221.276
MOL 文件
477888-48-5.mol
477888-48-5 結(jié)構(gòu)式
基本信息
中文別名
3-(2,5-二甲基-1H-吡咯-1-基)噻吩-2-羧酸 英文別名
Pyrrothiogatain3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophene-2-carboxylic acid
應(yīng)用領(lǐng)域
用途一
Pyrrothiogatain is a novel inhibitor of GATA family proteins, targeting the DNA-binding activity of GATA3 and other members of the GATA family, inhibiting the interaction between GATA3 and SOX4, significantly suppressing Th2 cell differentiation, without impairing Th1 cell differentiation, and inhibiting the expression and production of Th2 cytokines.