479347-85-8
479347-85-8 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-15066A | 6-CYANO-7-NITROQUINOXALINE-2;3-DIONE DISODIUM CNQX disodium | 479347-85-8 | 5 mg | 500元 |
| 2026/06/05 | HY-15066A | 6-CYANO-7-NITROQUINOXALINE-2;3-DIONE DISODIUM CNQX disodium | 479347-85-8 | 10 mg | 700元 |
| 2026/06/05 | HY-15066A | 6-CYANO-7-NITROQUINOXALINE-2;3-DIONE DISODIUM CNQX disodium | 479347-85-8 | 25 mg | 1400元 |
常見(jiàn)問(wèn)題列表
IC50: 0.3 μM (AMPA) and 1.5 μM (kainate receptor)
CNQX disodium (FG9065 disodium; 2-5 μM) reversibly blocks the Schaffer collateral and mossy fibre excitatory postsynaptic potential (EPSP), while sparing the fast and slow GABA-mediated inhibition in superfusion of hippocampal slices.
CNQX disodium (1-5 μM) produces a selective and dose-dependent reduction in the amplitude of the monosynaptic component of the DR-VRR recorded from lumbar spinal segments.
CNQX disodium (FG9065 disodium; 0.75-3 mg/kg; IP; 20 min before testing) decreased the number of cocaine responses in a dose-dependent manner during the first 15-min cocaine-free interval.
The bilateral infusion of CNQX disodium (0.5 or 1.25 μg) into the amygdala or dorsal hippocampus 10 min prior to a retention test partially blocks the expression of stepdown inhibitory avoidance in rats 24 h after training. CNQX disodium causes a complete blockade at a dose of 0.5 μg.
| Animal Model: | Male Wistar rats weighing 180-200 g |
| Dosage: | 0.75, 1.5, and 3 mg/kg |
| Administration: | IP; 20 min before testing |
| Result: | Decreased the number of cocaine (IV; 0.25 mg/infusion) responses in a dose-dependent manner during the first 15-min cocaine-free interval. |